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BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.
BeOne Medicines is seeking an accomplished scientific leader to serve as Director, Clinical Biomarkers & Translational Medicine within the Oncology organization. This individual will lead the development and implementation of integrated translational medicine and clinical biomarker strategies across a portfolio of innovative solid tumor programs spanning early- and late-stage clinical development.
The successful candidate will serve as the translational and biomarker lead for assigned programs, partnering closely with Discovery Research, Clinical Development, Clinical Pharmacology, Precision Medicine, Bioinformatics, Biostatistics, Regulatory Affairs, Diagnostics, Medical Affairs, and external collaborators to accelerate biomarker-driven drug development and enable data-driven clinical decision making.
Essential Functions of the Job:
Clinical Biomarker Strategy and Clinical Development
Lead the development and execution of integrated translational medicine and clinical biomarker strategies from First-in-Human through registration for assigned oncology programs.
Develop biomarker strategies supporting patient selection and enrichment; pharmacodynamic assessments, including target engagement; mechanism of action and mechanisms of sensitivity and resistance; dose optimization; prognostic and predictive biomarker development
Ensure biomarker plans are scientifically rigorous, operationally feasible, and aligned with overall clinical development objectives.
Integrate and interpret clinical, molecular, pharmacologic, and translational datasets to generate biological insights that inform program strategy, clinical development decisions, and portfolio prioritization.
Provide scientific leadership for biomarker-related regulatory activities.
Establish and manage strategic collaborations with academic investigators, contract research organizations, central laboratories, and diagnostic partners.
Represent BeOne Medicines at scientific meetings, external collaborations, and consortium activities.
Drive publication and presentation of high-impact translational and biomarker research in peer-reviewed journals and scientific congresses.
Experience
Minimum of five years of pharmaceutical or biotechnology industry experience in oncology drug development, including substantial experience leading clinical biomarker and translational medicine strategies.
Experience supporting companion diagnostic development is highly desirable.
Experience contributing to regulatory submissions involving biomarkers and precision medicine is preferred.
Scientific Expertise
Deep expertise in translational oncology and clinical biomarker science.
Working knowledge of modern translational technologies, including: next-generation sequencing (NGS), RNA sequencing, ctDNA, multiplex immunohistochemistry, digital pathology, proteomics, flow cytometry, single-cell technologies, emerging multi-omics approaches/data integration and computational biology
Leadership Competencies
The successful candidate will demonstrate:
Strategic scientific leadership with the ability to influence multidisciplinary teams in a global matrix environment.
Strong scientific judgment and data-driven decision-making.
Excellent written and verbal communication skills.
Proven ability to build productive external scientific collaborations.
Strong publication record and recognized scientific credibility within the oncology community.
Passion for innovation and advancing precision oncology to improve patient outcomes.
Knowledge of Mandarin is beneficial but not required.
Education Required:
PhD, MD, PharmD, or MD/PhD in Oncology, Molecular Biology, Immunology, Cancer Biology, Pharmacology, or a related scientific discipline.
Global Competencies
When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.
Fosters Teamwork
Provides and Solicits Honest and Actionable Feedback
Self-Awareness
Acts Inclusively
Demonstrates Initiative
Entrepreneurial Mindset
Continuous Learning
Embraces Change
Results-Oriented
Analytical Thinking/Data Analysis
Financial Excellence
Communicates with Clarity
Salary Range: $176,600.00 - $236,600.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.
We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact .
